Dr. Caligiuri describes his journey from being a liberal arts major at a college in upstate New York, to being a Stanford trained MD, to his current position as President of City of Hope National Medical Center. Along the way Caligiuri shares his thoughts on training to be a hematologist in the late ‘80s – at a time when there were no curative therapies, and such a calling was daunting at best – to his finding a cherished mentor that put him on the road to becoming one of the top NK cell experts in the world.